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Using AROMA for Continuous Bioreactor Monitoring in North Carolina

13th Dec 2022

Our AROMA technology excels at real-time, continuous measurement of volatile organic compounds (VOCs) for process control in critical industries. Scientists at the Golden LEAF Biomanufacturing Training and Education Center integrate AROMA-VOC into their small-scale yeast process to monitor methanol feed and volatile metabolites in bioreactors. The direct measurement of these VOCs allows the researchers to monitor cellular activity and gather data in real-time for development of automated process control. Such direct measurement eliminates potential contamination of the cell culture due to sampling, bypasses extensive offline analytical testing, and limits the waste of raw materials.

The Golden LEAF Biomanufacturing Training and Education Center (BTEC) is located on North Carolina State University’s Centennial Campus in Raleigh, NC. BTEC provides educational and training opportunities to develop skilled professionals for the biomanufacturing industry. Its facilities feature industry-standard equipment and a simulated cGMP (current Good Manufacturing Practice) pilot plant facility.

Entanglement Technologies continues to expand into new markets with their AROMA platform. Contact us to learn more about how AROMA can meet your VOC monitoring needs. We are committed to serving our customers in a variety of application areas.

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